omicron hospitalization rate vaccinated by ageomicron hospitalization rate vaccinated by age

552a; 44 U.S.C. These persons are excluded from the proportions of race/ethnicity but are included in other analyses. Stay up to date with your COVID-19 vaccines. Risk was especially high for people with severe combined immunodeficiency (HR, 6.2). Although the study was unable to directly estimate VE against hospitalization due to the small number of hospitalized cases, it found that over the entire study period, the incidence rate of hospitalization during the first 6 months of life was much lower among the infants whose mothers were vaccinated during pregnancy compared with those whose mothers were not vaccinated. The rate among adults who received a primary series, but no booster or additional dose, was three times the rate among adults who received a booster or additional dose. Hospitalization rates during peak Omicron circulation (January 2022) among unvaccinated adults remained 12 times the rates among vaccinated adults who received booster or additional doses and four times the rates among adults who received a primary series, but no booster or additional dose. Risk of hospitalisation associated with infection with SARS-CoV-2 lineage B.1.1.7 in Denmark: an observational cohort study. Our additional supplemental analysis suggests that pregnant persons who received at least one vaccine dose before pregnancy should complete their vaccination series during pregnancy to provide protection to their children during the first 6 months of life. As of January 26, 2022, 39.6% of Black persons received a primary vaccine series; of those, 43.9% of adults received a booster dose once eligible. If you need to go back and make any changes, you can always do so by going to our Privacy Policy page. This analysis describes weekly hospitalization rates during Delta- and Omicron-predominant periods. Perm. Among nonpregnant and pregnant adults aged 18 years, hospitalization rates were calculated overall, and by race/ethnicity and COVID-19 vaccination status. A previous study conducted before the Omicron-predominant period that showed increased risk for COVID-19associated hospitalization among certain racial and ethnic groups, including Black adults, and suggested the increased hospitalization rates were likely multifactorial and could include increased prevalence of underlying medical conditions, increased community-level exposure to and incidence of COVID-19, and poor access to health care in these groups (7). Hospitalisation associated with SARS-CoV-2 delta variant in Denmark. Infections are rare and can be severe or fatal, but so far scientists don't see genetic changes that pose an increased threat to people. We further classified vaccination status by the trimester within which the second dose or the unique dose (for those who received only one dose) was received. Other studies found similarly decreased proportions of severe outcomes among hospitalized patients with COVID-19 during this period (6).. Finally, the COVID-NET catchment areas include approximately 10% of the U.S. population; thus, these findings might not be nationally generalizable. Image, Download Hi-res CIDRAP - Center for Infectious Disease Research & Policy According to the CDC, hospitalization rates among the unvaccinated were 16 times higher in December overall. Baden, L. R. et al. China informed the WHO about the case, which involves a 53-year-old woman, on Feb 24. Use of trade names and commercial sources is for identification only and does not imply endorsement by the U.S. Department of Am. Overall, the study results support recommendations for vaccination during pregnancy to protect both mothers and their infants. COVID-19; IL-6 . COVID-19 hospitalization rates per 100,000 population by age and vaccination status, January 05 to February 01, 2023 Age group Age-specific rate per 100,000 among unvaccinated individuals Age-specific rate per 100,000 among those who received at least one booster dose Likelihood of unvaccinated individuals being hospitalized with Effectiveness of Covid-19 vaccines in ambulatory and inpatient care settings. Ainslie, K. E. C., Shi, M., Haber, M. & Orenstein, W. A. The TND analyses avoid this bias by limiting the analysis to infants who were tested for SARS-CoV-2. JAMA 327, 10871089 (2022). J. Obstet. Thus, this design better adjusts for healthcare-seeking behavior31,32, but it may also introduce other biases including selection bias33. SARS-CoV-2 infection can lead to severe illnesses and hospitalizations in children and infants2,3,4,5. During Omicron predominance, children aged <6 months accounted for 44% of hospitalizations among children ages 04 years3. Libby Reeg reports grants from the Michigan Department of Health and Human Services during the conduct of the study. Office of the Vice President for Research, University of Minnesota, Minneapolis, MN, 2023 Regents of the University of Minnesota. The average age of decedents was 83.3 years. By submitting a comment you agree to abide by our Terms and Community Guidelines. As a result, the number of total hospitalizations exceeds the sum of unvaccinated adults, adults who received a primary series without a booster or additional dose, and adults who received a primary series with a booster or additional dose. In this large study which included >30,000 infants, we found that receipt of at least two doses of mRNA COVID-19 vaccine during pregnancy was associated with a decreased risk of infants testing SARS-CoV-2 positive during their first 6 months of life. The results were unchanged when no adjustments for covariates were made (Supplemental Table3). adjudicated chart reviews. Abbreviations: COVID-NET = COVID-19Associated Hospitalization Surveillance Network; ICU=intensive care unit; IMV=invasive mechanical ventilation; LTCF=long-term care facility; NA = not applicable. Wkly. Effectiveness of COVID-19 Pfizer-BioNTech BNT162b2 mRNA vaccination in preventing COVID-19-associated emergency department and urgent care encounters and hospitalizations among nonimmunocompromised children and adolescents aged 5-17 yearsVISION Network, 10 states, April 2021-January 2022. SARS-CoV-2 infections can result in COVID-19associated hospitalizations, even among vaccinated persons. Publishers note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Klein, N. P. et al. Models were adjusted for the covariates listed above. M.G. SGN, HHW, NA, WH, MK, PB, AZ, JLB, MC, NAA, KH, RH, AC, GD, and ST curated the data. Atlanta, GA: US Department of Health and Human Services, CDC; 2022. Although hospitalization rates increased for all adults, rates were highest among unvaccinated adults and lowest among adults who had received a primary series and a booster or additional dose. If SARS-CoV-2 test date was missing, hospitalization admission date was used. All other authors declare no competing interests. TN, NMF, SFlax, MC, DDA, AMP, and ST conceptualised the work. Children and COVID-19: state data report. ***** An additional 172 (3.4%, 95% CI=2.7%4.2%) adults were partially vaccinated, 69 (0.9%, 95% CI=0.61.2) received a primary vaccination series <14 days before a positive for SARS-CoV-2 test result, and 186 (4.1%) had unknown vaccination status; these groups are not further described in this analysis. RESP-NET: COVID-19 Associated Hospitalization Rates among Adults Ages 65 Years and Older CDC's Respiratory Virus Hospitalization Surveillance Network (RESP-NET) shows that overall weekly rates of COVID-19-associated hospitalizations have declined for all age groups from a peak in December 2022. Get the most important science stories of the day, free in your inbox. Protection during both periods decreased as infants aged from 2 months to 6 months. Ousseny Zerbo. CAS J. Med. Weekly / March 25, 2022 / 71(12);466473. However, in contrast with the Norwegian study which reported that infants of mothers who were vaccinated had a 33% decreased risk of testing positive during the first 4 months of life during the Omicron period17, our study found a 13% reduced risk that was not statistically significant. * Overall rates are unadjusted; rates presented by racial and ethnic group are age-adjusted. Over the entire study period, the crude rate of hospitalization with a SARS-CoV-2 positive test was lower during the first 6 months of life among infants whose mothers received at least two doses . Among these infants, for our main analysis, we excluded 21,891 (35.2%) based on maternal exclusion criteria and 10,412 (16.8%) after applying infant exclusion criteria (Fig. KPNC members are similar to the broad catchment population in Northern California in terms of sociodemographic characteristics34. Models in this analysis were adjusted for the same covariates included in the primary analysis. Hospitalization rates among non-Hispanic Black adults increased more than rates in other racial/ethnic groups. Safety and efficacy of single-dose Ad26.COV2.S vaccine against Covid-19. Rep. 71, 2630 (2022). J. Med. Dis. Two recent papers claim there are no differences between surgical masks and respirators for preventing the spread of respiratory diseases like COVID-19 and flu, but the articles are deeply flawed. 40, e137e145 (2021). Evan J. Anderson reports grants from Pfizer, Merck, PaxVax, Micron, Sanofi-Pasteur, Janssen, MedImmune, and GlaxoSmithKline; personal fees from Pfizer, Medscape, Kentucky Bioprocessing, Inc., Sanofi-Pasteur, and Janssen, outside the submitted work; and institutional funding from the National Institutes of Health to conduct clinical trials of Moderna and Janssen COVID-19 vaccines. Wkly. When possible, CDC associates a persons primary vaccination series and booster dose with that person. We did not have genotyping data to confirm the variant that infected infants who tested positive and instead relied on state data regarding circulating strain predominance in the Northern California region. Infants were followed from birth until the first positive SARS-CoV-2 test by PCR at age 2, 4, or 6 months, with censoring due to death, health plan disenrollment, or end of follow-up (May 31, 2022). Vaccine 31, 21652168 (2013). 387, 109119 (2022). Arthur Reingold, Jeremy Roland, Ashley Coates, California Emerging Infections Program, Oakland, California; Breanna Kawasaki, Rachel Herlihy, Isaac Armistead, Madelyn Lensing, Jordan Surgnier, Sarah McLafferty, Colorado Department of Public Health & Environment; Ann Basting, Tessa Carter, Maria Correa, Daewi Kim, Carol Lyons, Hazhia Sorosindi, Connecticut Emerging Infections Program, Yale School of Public Health, New Haven, Connecticut; Emily Fawcett, Katelyn Ward, Jana Manning, Asmith Joseph, Allison Roebling, Chandler Surell, Stephanie Lehman, Taylor Eisenstein, Suzanne Segler, Grayson Kallas, Marina Bruck, Rayna Ceaser, Annabel Patterson, Sabrina Hendrick, Johanna Hernandez, Hope Wilson, School of Medicine, Emory University, Georgia Emerging Infections Program, Georgia Department of Public Health, Veterans Affairs Medical Center, Foundation for Atlanta Veterans Education and Research, Atlanta, Georgia; Jim Collins, Shannon Johnson, Justin Henderson, Sue Kim, Alexander Kohrman, Lauren Leegwater, Val Tellez Nunez, Sierra Peguies-Khan, Michigan Department of Health and Human Services; Kayla Bilski, Kristen Ehresmann, Richard Danila, Jake Garfin, Grace Hernandez, Kieu My Phi, Ruth Lynfield, Sara Vetter, Xiong Wang, Minnesota Department of Health; Daniel M. Sosin, Susan L. Ropp, Sunshine Martinez, Jasmyn Sanchez, Cory Cline, Melissa Judson, Florent Nkouaga, Mark Montoya, New Mexico Department of Health; Sarah Lathrop, Kathy M. Angeles, Yadira Salazar-Sanchez, Sarah A. Khanlian, Nancy Eisenberg, Dominic Rudin, Sarah Shrum Davis, Mayvilynne Poblete, Emily B. Hancock, Francesca Pacheco, New Mexico Emerging Infections Program; Yassir Talha, Celina Chavez, Jennifer Akpo, Alesia Reed, Murtada Khalifa, CDC Foundation, New Mexico Department of Health; Suzanne McGuire, Kerianne Engesser, Nancy Spina, Adam Rowe, New York State Department of Health; Sophrena Bushey, Virginia Cafferky, Maria Gaitan, Christine Long, Thomas Peer, Kevin Popham, University of Rochester School of Medicine and Dentistry, Rochester, New York; Julie Freshwater, Denise Ingabire-Smith, Ann Salvator, Rebekah Sutter, Ohio Department of Health; Sam Hawkins, Public Health Division, Oregon Health Authority; Tiffanie Markus, Katie Dyer, Karen Leib, Terri McMinn, Danielle Ndi, Gail Hughett, Emmanuel Sackey, Kathy Billings, Anise Elie, Manideepthi Pemmaraju, Vanderbilt University Medical Center, Nashville, Tennessee; Amanda Carter, Andrea George, Andrew Haraghey, Ashley Swain, Caitlin Shaw, Laine McCullough, Mary Hill, Ryan Chatelain, Salt Lake County Health Department, Salt Lake City, Utah; Alvin Shultz, Robert W. Pinner, Rainy Henry, Sonja Mali Nti-Berko, CDC; Elizabeth Daly, Council of State and Territorial Epidemiologists. Danino, D. et al. Several conditions, including cancer of the blood or bone marrow and dementia, were associated with HRs greater than 3. Provided by the Springer Nature SharedIt content-sharing initiative. However, infants aged <6 months are not currently eligible for any currently available COVID-19 vaccines and must rely on placentally acquired immunity from their mothers. Accessed March 10, 2022. It is possible that our exclusion criteria may have resulted in a final sample that may not be reflective of all KPNC infants. Am. Vaccination offers the best way to protect against COVID-19 and its complications. CDC graphs show in detail the protection vaccines gave from hospitalization. N. Engl. These data should be taken with a grain of salt. Furthermore, it was reassuring that both the cohort and the secondary TND yielded vaccine effectiveness estimates in the same direction. Sign up for the Nature Briefing newsletter what matters in science, free to your inbox daily. The report shows people catching Omicron are: 31% to 45% less likely to go to A&E. 50% to 70% less likely to be admitted to hospital for treatment. Evaluation of acute adverse events after Covid-19 vaccination during pregnancy. GD declares that his employer UK Health Security Agency (previously operating as Public Health England) received funding from GlaxoSmithKline for a research project related to influenza antiviral treatment. Nature. Pediatrics. All adults should stay up to date with COVID-19 vaccination to reduce their risk for COVID-19associated hospitalization. These proportions are lower compared with 47.3% of White persons who received a primary series and 54.5% of eligible adults who received a booster dose. Relative to the Delta-predominant period, Black adults accounted for a larger proportion of unvaccinated adults during the Omicron-predominant period, and age-adjusted hospitalization rates for Black adults increased to the highest rate among all racial and ethnic groups for any week during the pandemic. These cookies may also be used for advertising purposes by these third parties. The study was funded by the National Institute of Allergy and Infectious Disease grant # 1R01AI168373-01 to O.Z. You are using a browser version with limited support for CSS. We observed a similar pattern in vaccine effectiveness by trimester during the Omicron dominant period, however, estimates of vaccine effectiveness by trimester were imprecise and much lower than during the Delta period (Table3). 385, 13551371 (2021). Adults who received booster doses were classified as those who completed the primary series and received an additional or booster dose on or after August 13, 2021, at any time after completion of the primary series, and 14 days before a positive test result for SARS-CoV-2, as COVID-19associated hospitalizations are a lagging indicator and time passed after receipt of a booster dose has been shown to be associated with reduced rates of COVID-19 infection (https://www.nejm.org/doi/full/10.1056/NEJMoa2114255). 3501 et seq. Vaccine effectiveness of cell-culture relative to egg-based inactivated influenza vaccine during the 2017-18 influenza season. After adjusting for covariates, vaccination during pregnancy significantly reduced the risk of the infant testing SARS-CoV-2 positive by 84% (95% confidence interval [CI]: 66, 93) during the first 2 months of life, 62% (95% CI: 39, 77) during the first 4 months of life and 56% (95% CI: 34,71) during the first 6 months of life. Additional COVID-NET methods for determining vaccination status have been described previously. Razzaghi, H. et al. Omicron is super infectious, and about 20% of people in the United States over the age of 5 as well as all children under 5 remain unvaccinated. Access your favorite topics in a personalized feed while you're on the go. J. Med. KPNC has a comprehensive electronic health record system (Kaiser Permanente HealthConnect, a customized EPIC system), that captures detailed information on all medical services, including immunization, membership enrollment including place of residence, demographics, and pregnancy-related care from pregnancy onset to delivery, and beyond. SARS-CoV-2 delta VOC in Scotland: demographics, risk of hospital admission, and vaccine effectiveness. Vaccinated patients during the Delta wave were 37% (over with two doses), while during the Omicron wave they were 57%. Fully-vaccinated in this chart meant one dose of the J&J vaccine or two doses of Pfizer or Moderna. The study provides evidence that a previous omicron infection in triple-vaccinated individuals provides high amounts of protection against BA.5 and BA.2 infections. J. Pediatr. With the emergence of the SARS-CoV-2 Omicron variant in late 2021, Canadian public health case/contact testing was scaled back due to high infection rates with milder symptoms in a highly vaccinated population. ** Monthly incidence among adults who received booster or additional doses was calculated by summing the total number of COVID-19 patients with booster or additional doses hospitalized over all days of the month and dividing by the sum of adults with booster or additional doses in the underlying population for each day of the month. This method was also used for calculations in unvaccinated persons and those who received a primary series but not a booster or additional dose.. The prevalence of primary COVID-19 vaccination and of receipt of a booster dose were lower among Black adults compared with White adults. Foppa, I. M., Haber, M., Ferdinands, J. M. & Shay, D. K. The case test-negative design for studies of the effectiveness of influenza vaccine. After the emergence of the Omicron variant, the rate of COVID-19 hospitalizations in the United States was 10.5 times higher in unvaccinated adults and 2.5 times higher in those who were vaccinated but received no booster than in booster recipients, according to a new study. Our findings that receipt of at least two doses of COVID-19 vaccine during pregnancy was effective at protecting infants during the Delta period are similar to those reported in a recent Norwegian study showing that mRNA COVID-19 vaccination during pregnancy was associated with a 71% decreased risk of testing positive for SARS-CoV-2 in infants during their first 4 months of life during the Delta period17. ICU admission status was missing in 1.3% (weighted) of hospitalizations; these hospitalizations are included in other analyses. 20, 15225 (2016). Methods: This is a retrospective cohort study that was conducted in Israel's second-largest . To ensure stability and reliability of rates by vaccination status, data are presented beginning when 14 days have passed since at least 5% of the population of adults aged 18 years in the COVID-NET surveillance catchment area had received an additional or booster dose. Adults with a positive result whose SARS-CoV-2 test date was 14 days after the first dose of a 2-dose series but <14 days after receipt of the second dose were considered partially vaccinated. During the study period, the omicron variant experienced a rapidly increasing incidence, whereas the delta variant was experiencing a decreasing or less rapidly increasing incidence. Initial hospital data from England and Denmark also suggest Omicron cases are less severe. Mortal. Stay up to date with what you want to know. The results were published yesterday in JAMA Network Open. However, linking is sometimes not possible because CDC does not receive personally identifiable information about vaccine doses. Morb. The funders played no direct role in the study. The outcomes were the infants first positive nasal/throat swab for SARS-CoV-2 by PCR, and the first COVID-19-related hospitalization, occurring during the first 6 months of life and recorded in the electronic health record. The mean age at pregnancy onset was 31.62 years (standard deviation of 4.66 years). VE against hospitalization was not estimated because of the very small number of hospitalized cases. Infect. B., Lewis. Includes current treatment or recent diagnosis of an immunosuppressive condition or use of an immunosuppressive therapy during the preceding 12 months. We conducted secondary sensitivity analyses restricting the population to infants who received at least one SARS-CoV-2 PCR test. Gretchen Rothrock, California Emerging Infections Program; Millen Tsegaye, Colorado Department of Public Health and Environment; Julie Plano, Connecticut Emerging Infections Program, Yale School of Public Health; Kyle Openo, Georgia Emerging Infections Program, Georgia Department of Public Health Division of Infectious Diseases, School of Medicine, Emory University; Andy Weigel, Iowa Department of Health; Chloe Brown, Michigan Department of Health and Human Services; Erica Bye, Minnesota Department of Health; Wickliffe Omondi, New Mexico Emerging Infections Program, University of New Mexico; Alison Muse, New York State Department of Health; Christina Felsen, University of Rochester School of Medicine and Dentistry; Eli Shiltz, Ohio Department of Health; Nasreen Abdullah, Public Health Division, Oregon Health Authority; William Schaffner, Vanderbilt University Medical Center; Melanie Crossland, Salt Lake County Health Department. Further information on research design is available in theNature Portfolio Reporting Summary linked to this article. During the Omicron dominant period, maternal vaccination with at least two doses reduced the infants risk of testing SARS-CoV-2 positive by 43% (95% CI: 4, 69) during the first 2 months of life, 36% (95% CI:11, 55) during the first 4 months of life, and 41% (95% CI: 25, 53) during the first 6 months of life (Supplemental Table2). Zerbo, O. et al. Two new observational studies suggest that COVID-19 vaccination lowers long-COVID incidence and severity. As with previous variants, being vaccinated greatly protects you from severe disease with omicron. Characteristics and maternal and birth outcomes of hospitalized pregnant women with laboratory-confirmed COVID-19COVID-NET, 13 states, March 1August 22, 2020. To update your cookie settings, please visit the, https://doi.org/10.1016/S0140-6736(22)00462-7, Comparative analysis of the risks of hospitalisation and death associated with SARS-CoV-2 omicron (B.1.1.529) and delta (B.1.617.2) variants in England: a cohort study, https://www.who.int/news/item/26-11-2021-classification-of-omicron-(b.1.1.529)-sars-cov-2-variant-of-concern, https://www.cdc.gov/coronavirus/2019-ncov/science/science-briefs/scientific-brief-omicron-variant.html, https://www.mrc-bsu.cam.ac.uk/now-casting/report-on-nowcasting-and-forecasting-9th-december-2021/, https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1050999/Technical-Briefing-35-28January2022.pdf, https://www.research.ed.ac.uk/en/publications/severity-of-omicron-variant-of-concern-and-vaccine-effectiveness-, https://www.imperial.ac.uk/mrc-global-infectious-disease-analysis/covid-19/report-50-severity-omicron/, https://doi.org/10.1101/2022.01.11.22269045, https://doi.org/10.1101/2022.01.12.22269179, https://doi.org/10.1101/2022.01.20.22269406, https://doi.org/10.1101/2022.01.12.22269148, https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1054071/vaccine-surveillance-report-week-6.pdf, https://www.gov.uk/government/publications/investigation-of-sars-cov-2-variants-routine-variant-data-update, https://www.gov.uk/government/publications/nhs-test-and-trace-statistics-england-methodology/nhs-test-and-trace-statistics-england-methodology, https://www.england.nhs.uk/contact-us/privacy-notice/national-flu-vaccination-programme/, https://digital.nhs.uk/data-and-information/data-collections-and-data-sets/data-sets/emergency-care-data-set-ecds, https://digital.nhs.uk/services/secondary-uses-service-sus, https://www.england.nhs.uk/statistics/statistical-work-areas/covid-19-hospital-activity/, https://doi.org/10.1101/2021.08.13.21262014, View Large This was the highest age-adjusted weekly rate observed among any racial and ethnic group during the pandemic. Table 2. Blakeway, H. et al. The average death rate among Americans over age 65 who contract the flu has ranged between 1 in 75 and 1 in 160 in recent years, according to the C.D.C. Hospitalization rates during peak Omicron circulation (January 2022) among unvaccinated adults remained 12 times the rates among vaccinated adults who received booster or additional doses and four times the rates among adults who received a primary series, but no booster or additional dose. 1CDC COVID-19 Emergency Response Team; 2General Dynamics Information Technology, Atlanta, Georgia; 3California Emerging Infections Program, Oakland, California; 4Career Epidemiology Field Officer Program, CDC; 5Colorado Department of Public Health & Environment; 6Connecticut Emerging Infections Program, Yale School of Public Health, New Haven, Connecticut; 7Emory University School of Medicine, Atlanta, Georgia; 8Georgia Emerging Infections Program, Georgia Department of Public Health; 9Atlanta Veterans Affairs Medical Center, Atlanta, Georgia; 10Iowa Department of Public Health; 11Michigan Department of Health and Human Services; 12Minnesota Department of Health; 13New Mexico Emerging Infections Program, University of New Mexico, Albuquerque, New Mexico; 14New York State Department of Health; 15University of Rochester School of Medicine and Dentistry, Rochester, New York; 16Ohio Department of Health; 17Public Health Division, Oregon Health Authority; 18Vanderbilt University Medical Center, Nashville, Tennessee; 19Utah Department of Health. J. Med. A free-text field for other types of residences was examined; patients with an LTCF-type residence were also categorized as LTCF residents. The proportion of hospitalized adults who received booster or additional doses increased from 1.3% during the Delta-predominant period to 13.4% during the Omicron-predominant period (p<0.01)***; among these, 10.7% were long-term care facility residents and 69.5% had an immunosuppressive condition. Black adults accounted for 25.2% of all unvaccinated persons hospitalized during the Delta-predominant period; that proportion increased by 23%, to 31.0% during the Omicron-predominant period. N. Engl. Sample sizes presented are unweighted with weighted percentages. These cookies perform functions like remembering presentation options or choices and, in some cases, delivery of web content that based on self-identified area of interests. During the Omicron-predominant period, overall weekly adult hospitalization rates peaked at 38.4 per 100,000, exceeding the previous peak on January 9, 2021 (26.1) and the peak rate during the Delta-predominant period (15.5) (Figure 1). References to non-CDC sites on the Internet are Data from the COVID-19Associated Hospitalization Surveillance Network (COVID-NET) were analyzed to compare COVID-19associated hospitalization rates among adults aged 18 years during B.1.617.2 (Delta; July 1December 18, 2021) and Omicron (December 19, 2021January 31, 2022) variant predominance, overall and by race/ethnicity and vaccination status. The cohort analyses may be biased toward the null if some infected infants were misclassified as uninfected due to the absence of a SARS-CoV-2 test result in the medical record. In the meantime, to ensure continued support, we are displaying the site without styles the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Rates are calculated using the CDC National Center for Health Statistics vintage 2020 bridged-race postcensal population estimates for the counties included in surveillance. We calculated VE as 100% multiplied by 1- OR. Buchan, S. A. et al. Our analysis . From Jan 1 to Mar 16, 2022, when Omicron was predominant, 4,781 (0.02%) of 19,473,570 booster recipients died of COVID-19, and 58,020 (0.3%) died of other causes. This work was supported by grants from the UK Research and Innovation (UKRI) Medical Research Council (NMF, WH, SB, EV, ACG [Centre for Global Infectious Disease Analysis; MR/R015600/1], DDA, AMP [MC/UU/00002/11], and SRS [MC/UU/00002/10]); Medical Research Council UKRIDepartment of Health and Social Care National Institute for Health Research (NIHR) COVID-19 rapid response call (NMF, SB [MR/V038109/1], TN, AC, DDA, and AMP [MC/PC/19074]); the NIHR Health Protection Units in: Modelling and Health Economics (NMF, WH, SB, EV, AC, and ACG [NIHR200908]), Behavioural Science and Evaluation (AC and DDA), and Respiratory Infections (JLB); Wellcome Trust (SFunk and SA [210758/Z/18/Z]); philanthropic funding from Community Jameel (NMF, WH, SB, and EV); and the UKRI Engineering and Physical Sciences Research Council (SFlax [EP/V002910/2]).
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